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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
32.12
Human Site:
S764
Identified Species:
64.24
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
S764
T
D
E
Y
L
D
L
S
A
P
F
E
Q
Y
S
Chimpanzee
Pan troglodytes
XP_521622
819
91776
S771
N
E
E
Y
L
D
L
S
Q
P
L
E
Q
Y
S
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
S764
T
D
E
Y
L
D
L
S
A
P
F
E
Q
Y
S
Dog
Lupus familis
XP_545926
833
90729
S791
T
D
E
Y
L
D
L
S
V
P
F
E
Q
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
S759
T
D
E
Y
L
D
L
S
V
P
F
E
Q
Y
S
Rat
Rattus norvegicus
Q04589
822
91806
S770
N
Q
E
Y
L
D
L
S
M
P
L
D
Q
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
S758
T
D
E
Y
L
D
L
S
V
P
F
E
Q
Y
S
Frog
Xenopus laevis
O42127
802
89497
S754
T
N
E
Y
L
D
L
S
V
A
F
E
Q
Y
S
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
S752
T
D
E
Y
L
D
L
S
V
P
F
E
Q
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
V685
R
P
P
F
T
E
I
V
E
Y
M
D
K
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
E944
E
T
I
E
G
S
Q
E
F
N
D
Q
F
F
S
Sea Urchin
Strong. purpuratus
Q26614
972
110463
E928
N
Q
D
Y
L
D
L
E
A
V
G
D
A
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
73.3
100
93.3
N.A.
93.3
60
N.A.
N.A.
93.3
80
93.3
N.A.
0
N.A.
6.6
33.3
P-Site Similarity:
100
80
100
93.3
N.A.
93.3
66.6
N.A.
N.A.
93.3
86.6
93.3
N.A.
33.3
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
25
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
9
0
0
84
0
0
0
0
9
25
0
9
0
% D
% Glu:
9
9
75
9
0
9
0
17
9
0
0
67
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
9
0
59
0
9
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
84
0
84
0
0
0
17
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
25
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
67
0
0
0
9
0
% P
% Gln:
0
17
0
0
0
0
9
0
9
0
0
9
75
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
75
0
0
0
0
0
0
84
% S
% Thr:
59
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
42
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
84
0
0
0
0
0
9
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _